Sentence examples for a bypass of cellular from inspiring English sources
Progression to malignancy correlates with a bypass of cellular senescence.
Understanding the molecular mechanisms and biological consequences of genetic changes occurring during bypass of cellular senescence spans a broad area of medical research from the cancer field to regenerative medicine.
This is because, when organisms are young, senescence acts as a tumor suppressor mechanism through the removal of genetically unstable cells or cells that have acquired an oncogenic mutation, by inhibiting their proliferation (oncogene-induced senescence) (Campisi, 2005, 2013); replicative immortality gained through the bypass of cellular senescence is thus a key hallmark of cancer cells.
A bypass of downtown Midland was opened in 1934.
A bypass of Glasgow was completed in the 1990s.
The three routes head south along a bypass of Charles City.
A bypass of Saginaw was completed by 1953.
Planning to extend the South Bend Bypass northward into Michigan as a bypass of Niles began in 1967.
At this point, the precursor lesions display both cellular and molecular changes, which are characteristic of senescence and their progression to cancer, an outcome that requires bypassing of this cellular mechanism.
As an alternative explanation to the oncogene (and also perhaps non-oncogene) addiction, Dean Felsher proposed that oncogene activation may induce a state of cellular amnesia, which allows cells to bypass surveillance mechanisms and, therefore, permits unregulated cell proliferation (Felsher 2008).
