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This is a very narrow definition as it does not take into consideration the location of the event or the function in a broader, pathway or network context.
These pathways include those identified in the canonical pathway analysis (cell cycle regulation, apoptosis, and LPS-stimulated MAP kinase signaling) as well as the nuclear factor kappa B (NF-κB) signaling pathway and a broader pathway of endothelial barrier integrity that includes VEGF signaling.
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All these data clearly support that the UCN3 gene plays an important role in regulation of adipocyte metabolism through a broad pathway.
From a mechanistic point of view, a broad pathway of fibril formation could be schematized by one of three straightforward models: i) the "refolding" model, in which self-propagating conformational rearrangements must occur in order to adopt a structure competent for self-assembly into fibrils.
The neural conduit for medullary control of laryngeal adductor muscles actions is contained within a broader neural pathways controlling cough and swallowing [ 46].
Whether additional, broader pathways are controlled by LRH-1 and/or PLK3 in response to stress remains an open question.
As an important tributary of a broader sustainable development pathway, DRR must be integrated with the development process in the communities.
While we cannot ascertain what represents the ancestral state, it is tempting to speculate that a broader mRNA degradation pathway preceded the development of the more specialized splicing mechanism.
There was a broader range of pathways that had indicative trends (q-value < 0.3) based on GSEA.
However, the Streets to Homes program uses intensive case management (ICM) rather than ACT as the service delivery model and serves a broader population than Pathways to Housing, as it includes all those who are on the streets rather than targeting only those with severe mental illness.
Scattered across the broad pathway, men in suits talk into mobile phones.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com