Exact(3)
Although originally discovered in the pituitary gland and named for its effects on pigmentation more recent studies revealed that α-MSH interacts with different types of cells such as macrophages, neutrophils or epidermal cells resulting in a broad spectrum of functions including anti-microbial, anti-inflammatory, as well as immunomodulatory activities [4] [9].
S100 proteins are a family of small Ca2+-binding proteins [ 1] which share a broad spectrum of functions including regulation of enzyme activity, Ca2+-homeostasis, and interaction with components of the cytoskeleton.
In 2006, it was renamed Translocator Protein 18 kDa (TSPO) to better represent the emerging understanding of a family of highly conserved integral membrane proteins found from Archaea to plants and humans, with a broad spectrum of functions, including steroid and porphyrin transport and regulation of apoptosis, inflammation, metastatic cancer, and cardiovascular diseases.
Similar(57)
Recent insights suggest that MMPs may also have a broader spectrum of functions including regulation of the inflammatory response, for example through effects on chemokine and cytokine signaling and by release of neoepitopes from the ECM (Pearce and Shively 2006).
Repeated domains in proteins are associated with a broad spectrum of functions.
Such a broad spectrum of functions is compatible with the proposed biochemical functions of the AN protein.
Bone morphogenetic proteins (BMPs) are multifunctional secreted growth factors regulating a broad spectrum of functions in numerous systems.
M6A modification affects a broad spectrum of cellular functions, including maintenance of the pluripotency of embryonic stem cells (ESCs) and the reprogramming of somatic cells into induced pluripotent stem cells (iPSCs).
Both toxins influence a broad spectrum of cellular functions, including changes in vascular permeability leading to barrier dysfunction manifested as tissue edema and pleural effusions [5].
In addition to the regulation of cell movements and adhesion, Snail factors have a broad spectrum of biological functions, including the regulation of cell proliferation and survival (Vega et al, 2004).
Proteins belonging to the profilin family of actin-binding proteins are considered to be important control elements for actin polymerization and have been linked to a broad spectrum of cellular functions, including cell migration.
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