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A broad screen of whole cell sonicate from B. garinii against human sera followed by de novo sequencing identified the hypothetical protein BG0407 (Genbank AAU07257) as a novel fH-binding protein [ 59].
To examine binding to individual glycans, fluorophore-labelled CL-K1 was used to probe a broad screen of mammalian carbohydrates using the Core H Glycan array technology facility at The Consortium for Functional Glycomics [ 16].
As a broad screen of activities, the resident intruder assay (Bolivar et al., 2007) was modified to use video recording to quantify all distinct behaviours of cuprizone-treated and non-treated resident mice in the presence and absence of an intruder mouse in combination with analysis of movement to assess overall activity level and overt neurological differences.
Because little detailed information is known about the binding specificities of rat ficolins, we examined their lectin properties towards a broad screen of endogenous and exogenous carbohydrates using the Core H Glycan array technology facility at The Consortium for Functional Glycomics, Emory University GAA, USA).
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developing CBA and evaluate the soft effects with MCA; developing a MCA for a broad screening of options and evaluate public expenditures and consumer surplus with CBA.
The goal of our study was a broad screening of polymeric materials to find out those with similar structure and functional principles to biological examples known from insect smooth attachment systems.
Therefore, the joint use of the methodologies might be done in two ways: 1) developing CBA and evaluate the soft effects with MCA; 2) developing a MCA for a broad screening of options and evaluate public expenditures and consumer surplus with CBA. .
A broad screening of bacteria and fungi by Gadler and Faber in 2007 for potential sulfatase activity on 2-octyl sulfate resulted in several highly active strains from Pseudomonas sp., together with many inactive candidates (Gadler and Faber 2007b).
A broad screening of diaphragm from mechanically ventilated rats, using Western blots, identified several additional proteins with notable induction patterns that were also modulated by treatment with R548, indicating that these were positioned downstream of JAK signaling and could contribute to diaphragm dysfunction (Fig. 2 E).
The selection of clinically promising HIF-1 targeting agents will require a broader screen of several substances in a panel of cell lines in vitro with confirmation of results in experimental in-vivo models.
Two of these residues (Lys and Lys) were previously mutated by Mao and colleagues [ 38] in a broader screen of positive charged residues in/near TM2 with similar results to those obtained in the present study.
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