Considering that the HLA status of our study patients and control individuals was unknown, these peptides were chosen as being recognized by a broad range of class I molecules [ 18].
The undesirable effects of inhaled corticosteroids comprise a broad range of class-related adverse events that include hoarseness/dysphonia, candidiasis of the mouth and throat, adrenal suppression, growth retardation in children and adolescents, decreased bone mineral density, cataract, glaucoma, hyperglycaemia, contusions and pneumonia (in patients with chronic obstructive pulmonary disease).
Some, including LaLande, the former coach, favored a consolidation with nearby Grand Lake High, arguing that it would save money, allow for a broader range of classes to be taught and provide a reliable stream of athletes.
The proposed GFSs can capture the shapes of a broad range of object classes without the need of large a-priori shape databases.
In addition, the projects at CHDR usually are of relatively short duration while covering a broad range of drug classes, thus providing a lot of variation in the work.
Although several excellent standard software packages are available for ODEs, there are - for good reasons - no standard numerical continuation toolboxes available for partial differential equations (PDEs), which cover a broad range of different classes of PDEs automatically.
Because of this, numerous protocols for metabolite analysis have been developed to cover a broad range of compound classes, which are frequently characterized by the following workflow, as summarized in Figure 1: (i) material of choice, (ii) sample preparation and extraction, (iii) analytical methods, (iv) data processing and (v) data analysis and interpretation.
What is unprecedented is that these developments have occurred across a broad range of asset classes and across many countries at the same time.
