Authors of the white papers should be allowed sufficient time and opportunity to finish their work, preparing their papers for submission for independent review by a broad panel of independent scientists and policy experts.
Both compounds were tested against a number of TRP channels as well as against a broad panel of other non-related receptors and channels.
Both are known to play a role in multiple drug resistance (MDR), a syndrome by which cancer cells become resistant to a broad panel of cytotoxic compounds [5].
The statistically soundness of GP models is observed for a broad panel of kernels, among which the NP and radial kernels display the best results.
Tissue explants were infiltrated with methacrylate resin, sectioned and stained with a broad panel of inflammatory markers in addition to conventional histological stains.
On the other hand, these cells also secrete a broad panel of growth factors and cytokines that can exert trophic effects on surrounding tissues.
Olcegepant was shown to be a pure antagonist for the human CGRP receptor and to be selective against a broad panel of enzymes and receptors such as calcitonin, amylin or adrenomedullin receptors [54].
pK i values were determined by radioligand binding to a broad panel of receptors, channels and transporters at CEREP (Paris, France) [43] aActivity was tested against the following related TRP channels: rTRPV2, hTRPV4, hTRPA1, cTRPM8.
Compounds 11, 12, 13 and 14 were evaluated for their in vitro antiviral activity against HIV-1-, HIV-2-, HBV- and a broad panel of DNA viruses, and found to exhibit moderate to potent antiviral activity.
We have designed a broad panel of isogenic viruses encoding defined mutants of HIV-1SF2 Nef and analyzed their biological activity in the context of productive HIV-1 infection.
Our findings indicate that combined nasal-throat swabs are the specimens of choice for sensitive molecular detection of a broad panel of viral agents.
