Exact(1)
Lifestyle is a broad expression that includes diet, physical exercise, and psychological and socio-economic factors, each of which must be taken into due consideration because of their intertwining influences, which may be a barrier to healthy changes at both the individual and population levels.
Similar(59)
FoxO1 may have a vital role in a number of functions given its broad expression that may relate to astrocyte survival [ 38], modulation of embryonic endothelial stem cell survival [ 39], regulation of ischemic brain injury [ 10], vascular disease [ 40], and motor and memory pathways in the striatum and subregions of the hippocampus [ 36].
The calpain family comprises a heterogeneous group of cysteine proteases with a broad expression pattern that includes multiple isoforms that are both ubiquitous and tissue specific.
The transcription factor pitx2, described as a putative odontogenic-commissioning gene [ 12, 13, 15], has a broad expression pattern that encompasses both the developing tooth unit and the inter-tooth region, marking the extent of the dental-competent oral epithelium, including regions of future tooth rows.
BATF2, a novel tumor suppressor and type I IFN-inducible early response gene, has a broader expression profile that includes hematopoietic and non-hematopoietic tissues [ 2].
Usually a broad expression profile indicates pleiotropic functions that would constrain divergence of coding genes [ 19, 90].
They tried to explain this unexpected phenomenon using the 'preferential attachment' hypothesis suggested by Albert et al. (2002), in which genes expressed in the more recent cortical region are more likely to be expressed broadly because they tend to be the genes that already have a broad expression breadth in the subcortical region [ 27, 39].
It is indicated that ChemR23 has a broad expression in various cell types, including spinal dorsal horn neurons [ 17].
RT-PCR analysis indicated that CCS52A2 had a broad expression profile including roots, rosette leaves, stem, cauline leaves, inflorescences and siliques.
They only analyzed genes with endosperm-specific expression in the seeds with the exclusion of genes having a broader expression pattern in seeds, suggesting that endosperm-specific imprinted genes more often showed a higher rate of sequence evolution than their duplicated partners.
Within the skin, GPNMB/OA has been proposed to be expressed specifically in melanocytes [9], while others suggest a broader pattern of expression that includes keratinocytes, melanocytes and Langerhans cells [7].
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