Sentence examples for a broad dose from inspiring English sources

In studies designed to explore this general response over a broad dose range, female Swiss mice were administered six different diets containing Pb acetate 1 day after mating.

Effects of subcutaneous administration of two selective melanin-concentrating hormone MCH1 receptor antagonists, labeled A and B were examined over a broad dose range (1, 3, 10, 20, 40 mg/kg) on rat sleep wake architecture.

These doses were chosen to permit an evaluation of multiple biodosimetric assays over a broad dose range.

The derived estimates were based on a large and homogeneous cohort with a broad dose range.

Next day the cells were treated with gefitinib, RAD001 and combination of both drugs at a fixed molar ratio over a broad dose range to establish growth curves for a 72 h and 144 h read-out.

Phase 1 trials with a broad dose range (400 to 1600 mg/day) revealed a low drug exposure in the brain [ 66], while phase 2 trials narrowed this spectrum (400 800 mg, twice daily) and showed trivial benefits on function with the lowest dosage (400 mg).

Given its pharmacodynamic properties, IDeg offers a broad dosing window, allowing for flexible dose administration, if required.

A broad dosing schedule was included in this trial.

The crisis of Islam could use a broader dose of Turkish give-and-take.

In contrast, a broader dose range of I'm-Yunity™ (PSP) affects the expression of the p65 subunit.

At the end of phase IIa, it would also be relevant to include patient data from phase I trials, and at submission it would be relevant to include, both the larger phase III and the phase IIb dose-finding trials, which typically span a broader dose range.