Sentence examples for a broad alteration of from inspiring English sources

Second, the directions taken by technological trajectories and aggregate demand in advanced economies seem to point toward a broad alteration of the balance of locational advantages for production fragments, decreasing the weight of labor costs and augmenting the relevance of local availability of other complementary intangible assets.

However, their study does not provide a basis for recommending a broad alteration of blood lead screening strategies.

Together these findings confirmed that MB tumors harbor abnormal levels of distinct NOTCH ligands, which likely results in a broad alteration of the fine-tuning regulation of the signaling pathway.

The broad alteration of the metabolic profile observed in wild type worms upon prohibitin depletion, prompted us to examine its effect on the H NMR profile of daf-2 mutant animals.

It should be noted that such a response does not represent the broad alterations of expression profile generally observed in pre-mortal conditions, as no mortality occurred and all fish gradually recovered when water temperature was backed to 16°C [ 42].

It is reasonable to assume that the RA pathogenesis is influenced by broad alterations of gene expression in general.

Discrepancies between the mRNA and protein expression for several jun/fos genes suggest broad alterations of post-transcriptional processes in the RA SM.

However experimental work suggests that broader alterations of processing style may also have an impact on related cognitive processes (Watkins and Moulds 2005).

Sleep-disordered breathing represents a broad spectrum of alterations, ranging from habitual snoring, through obstructive hypoventilation to obstructive sleep apnea-hypopnea syndrome, and produces breathing and architecture anomalies during sleep.

Here we show that mutant mice in which SRF is selectively ablated in adult post-mitotic myofibers develop a broad spectrum of alterations similar to those which have been described in age-advanced skeletal muscles.

The work described thus far produced a collection of mutant strains carrying a broad spectrum of alterations in the photosynthetic apparatus that was useful for isolating strains with a specific phenotype of interest.