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Ayesha Siddiqa told me, "There is a breakdown of effective government.
In patients in a vegetative state, who were open-eyed, behaviourally awake but unresponsive, transcranial magnetic stimulation triggered a simple, local response indicating a breakdown of effective connectivity, similar to the one previously observed in unconscious sleeping or anaesthetized subjects.
In contrast, after loss of consciousness induced by general anaesthesia (Ferrarelli et al., 2010), TMS pulses invariably produced a simple response that remained localized to the site of stimulation, indicating a breakdown of effective interactions among thalamocortical modules.
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A similar breakdown of effective connectivity was observed during slow wave sleep early in the night (Massimini et al., 2005), when subjects report little or no conscious content upon awakening (Hobson et al., 2000).
The results of Group II experiments are also reported in Fig. 3 and indicate that the breakdown of effective connectivity observed in patients in a vegetative state can be reversible and that a substantial improvement in the brain's ability to sustain internal communication occurs at an early stage during recovery of consciousness, before reliable communication can be established with the patient.
The injection of a steroid into the keloid can be effective in some patients, leading to a breakdown of the collagen deposit and a flattening of the growth.
MIT invested great resources and hope into the CCCC; the effective abandonment of its report represents a breakdown of the institutional process.
A breakdown of cultural authority.
Doll gave a breakdown of the list.
A breakdown of law and order.
"What we see are institutional breakdowns, not a breakdown of the system itself".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com