Sentence examples for a bleeding model from inspiring English sources

More importantly, using a bleeding model that closely mimics the clinical morbidity of hemophilic arthropathy, mice that received the scAAV8.FIXR338L vector developed minimal histopathological findings of synovitis after hemarthrosis, when compared with mice that received identical doses of wild-type FIX vector.

A study evaluating the effects of rFVIIa and PCC in a rabbit bleeding model failed to show reversal of rivaroxaban-induced bleeding in spite of improvement in laboratory parameters [ 29].

To model a persistent bleeding rat (171 g, n = 1), heparin (1000 IU/kg body weight) was injected via the tail vein just before injection of 18F-FDG-labeled RBCs, whereas no heparin was used for a temporary bleeding model (170 g, n = 1).

We evaluated the hemodynamic efficacy of the OTSC in an established bleeding model.

We are, however, aware that we did not investigate an uncontrolled bleeding model, limiting interpretation of these specific results with regard to DCR.

Fig. 5 18F-FDG-labeled RBC PET in a temporary intraabdominal bleeding model.

The radioactivity appeared soon after the manual puncture of the colonic wall (22 min), and then it reached a plateau about 5 min later Fig. 6 18F-FDG-labeled RBC PET in a persistent intraabdominal bleeding model.

In a rat tail bleeding model, FEIBA significantly reduced the bleeding time associated with dabigatran.

To investigate the potential of the nanocomposite to stop otherwise lethal bleeding, a standardized liver bleeding model was applied (Supporting Information, Figure S10).

rFVIIa has also been shown to reduce dabigatran-induced bleeding in a rat tail bleeding model with partial normalisation of the APTT.

In this regard, a potential agent (PER977) has demonstrated effective reversal of factor Xa inhibition in vitro and in a rat-tail bleeding model [ 58, 59].