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The discovery of the epigenome provides an explanation, at the molecular level, for why and how early positive and negative social experiences give rise to a biological memory that can have lifelong impacts.
Epigenetic programming is the process by which cells retain a biological memory of environmental events that occur during critical periods of development.
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Therefore, for networks in which synapses are generally comprised of multiple individual contacts, the argument of Fusi et al. [16] may not suffice to rule out bistability mediated by SRR as a viable biological memory storage mechanism.
Medical applications of this material expanded and Ni-Ti shape-memory alloy was widely regarded as a "valuable biological memory material" [ 32].
It is plausible that this cyclic mechanism for controlling bistability of synaptic weight may correspond to a mechanism for biological memory forgetting, making synapses available for formation of new memories.
A model of biological memory will improve our ability to interpret how cells respond to signals as they do, and may provide insights into their rational manipulation.
In conclusion, repeated exposure to traumatic events over the lifetime seems to induce long-lasting changes in the regulation of inflammatory processes that constitute a form of biological memory of the stressor and might lead in the long run due to self-perpetuating processes to the development of various physical diseases.
Whereas Inga, a healthy adult, relies on her biological memory, Otto, a patient with Alzheimer's disease, must consult his notebook in order to retrieve the address of the Museum.
Pattern completion, the ability to retrieve complete memories on the basis of incomplete sets of cues, is a crucial function of biological memory systems.
The dynamics illustrated in Figs. 5 and 7 do not yet represent a satisfactory system for biological memory storage, because those dynamics have no mechanism for reversing L-LTP and forgetting memories.
The system control including biological memory should incorporate an indispensable algorithm for resolution of multiple responses to ensure content-addressable access.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com