TIR1 contains a binding pocket that can bind IAA and can also bind two auxin analogs, 2,4-D and 1-napthalenacetic acid (1-NAA) [10], [15], [63].
A binding pocket that is likely to bind a ligand will have an Sscore greater than 0.8 and a Dscore greater than 0.83 [44] 44].
Binding of putrescine introduces two positive charges into a binding pocket that contains three conserved acidic residues.
The results from the molecular modelling studies suggest that 2-BFI binds to B-CK in a cleft or a binding pocket adjacent to the active site.
Then, a binding pocket was generated.
Previous approaches targeted a binding pocket where derivatives of ligands displayed a defined structure-activity relationship.
FhGAPDH lacks a binding pocket which has been exploited in the design of novel antitrypanosomal compounds.
We consider the types and number of pseudocenters as descriptor for the physico-chemical properties of a binding pocket.
Traditional nuclear medicine ligands were designed to target cellular receptors or transporters with a binding pocket and a defined structure activity relationship.
In our study and as the FTIR spectra have showed, two carbonyl oxygen atoms as well as the amide oxygen can provide a binding pocket for Hg2+.
In this work, we tried to use an abasic site (AP site) that was embeded in a double-stranded DNA as a binding pocket for fisetin.
