Sentence examples for a big problem since from inspiring English sources

Sanitation in hundreds of slums in Rio de Janeiro has been a big problem since the 50s.

This is a big problem since her flight has been booked and paid for and she can't miss the dress rehearsal.

"Central Italy has 500 landraces, mostly maintained by aged farmers and gardeners, and that is a big problem since there is a chance these crops will be lost within a generation," said Valeria Negri, a plant scientist at the University of Perugia.

That's a big problem, since these names happen to dominate the market.

They serve to significantly shrink their pool of interested investors, which is a big problem, since these bonds mature every 30 days or so.

Usually that doesn't present a big problem, since, for example, competitive Call of Duty leagues are pretty much all on console.

Bootlegging, the shipping of cigarettes into New York without paying state taxes, has become a bigger problem since the state doubled its tax in March.

Name disuse is symptomatic of a bigger problem, since cities have also been losing their family and business "customers" to the suburbs.

It must have been a big problem, indeed, since when the belt started turning at the carousel at Kennedy Airport, it turned out that not a single checked bag had made it onto the plane.

A big problem ever since Daimler and Chrysler merged in November 1998 has been the refusal of Mercedes executives to share vehicle underbodies and other parts with Chrysler so as to achieve greater economies of scale.

These infections comprise a big problem nowadays, since they are increasingly common in immunosuppressive diseases, in which these fungi turn into opportunistic pathogens potentially responsible for high mortality [ 5, 6].