The phrase "a big difference when it comes" is correct and usable in written English.
It can be used to highlight a significant distinction in a specific context or situation.
Example: "There is a big difference when it comes to the quality of service provided by different companies."
Alternatives: "a significant difference regarding" or "a major distinction in terms of".
Lead time also makes a big difference when it comes to breaking through the advertising clutter and competing entertainment options.
Flood proofing a home against future events by putting in solid flooring and electrical wiring half way up the wall will also make a big difference when it comes to rebuilding if the worst happens.
Our team of testers – with various different hair types, from dense, tight curls of afro-textured hair to pencil-straight east-Asian hair (type makes a big difference when it comes choosing a good dryer) – put the top brands through their paces, judging how fast they worked, how heavy they felt and most importantly how they made hair feel.
Having low levels of IGF-1 can make a big difference when it comes to avoiding some of the most common degenerative illnesses in later life, and we're now getting some fresh insights into how this might work for Alzheimer's disease.
Human connection is no Instagram hack, but it makes a big difference when it comes to user engagement.
But this alone could make a big difference when it comes to finding good candidates for your company.
These small fixes can make big differences when it comes to damage mitigation.
Not having a typical office setup is clearly the biggest difference when it comes to working from home.
Milliseconds make a difference when it comes to chat.
"It makes such a big difference when your pitching comes around," said Andy Pettitte, who is scheduled to start the fourth and final game of the series today.
Shola made a big difference when he came on and I thought we deserved to win it in the end.
