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The phrase "a big cause of" is correct and usable in written English.
It can be used to indicate a significant factor or reason behind a particular outcome or situation.
Example: "The lack of funding is a big cause of the project's delays."
Alternatives: "a major factor in" or "a significant reason for".
Exact(51)
It is a big cause of pneumonia.
That response has been a big cause of the declining influence of environmentalists in Britain.
Bad ballot design requirements are clearly a big cause of this, as is voter education".
Since a big cause of Europe's high unemployment is high labour taxes, it is doubly damaging.
Overloaded intersections cause lots of noise and pollution, and are a big cause of traffic delay.
Second, sluggish demand overseas is a big cause of the deficit, so it is reversible.
Similar(9)
It is possible that globalisation is becoming a bigger cause of American wage inequality.
Many psychiatric patients suffer from other physical conditions, they add, which are a bigger cause of early death than suicide.
This indicates that burnout may be an even a bigger cause of medical error than a poor safety environment, Tawfik said.
They point out that the recent Global Burden of Disease study, published by the Lancet, found eating too little fruit and vegetables was a bigger cause of ill-health in the UK than drinking too many colas.
Chileans and Venezuelans see poverty as a bigger cause of discrimination than gender or ethnicity, according to researchers from Oxford University.Several countries have experimented with schemes that connect lonely old people and deprived youth.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com