Sentence examples for a better potency from inspiring English sources
This is the first time that an inhibitor is reported to have a better potency for EDN than for RNase A. The crystal structure of EDN 11c complex reveals the structural basis of its potency and selectivity providing important guidelines for future structure-based inhibitor design efforts.
The latter were merged in a single compound that exhibited a 200-fold better potency than the original hit compound.
Synagis had a 180-fold better potency than the derived Fab due to bivalent binding, indicating that the formatted VHH RSV-D3, which competes with and therefore recognizes the same region as Synagis, must achieve its greatly increased potency by a different avid interaction.
In our earlier work, such an extract showed better potency than artemisinin alone against both chloroquine-sensitive and -resistant parasites.
Analogue 12, with a 10 residue peptide graft, is also a full agonist with much better potency (chemotaxis peak at 10 nM).
We have recently reported that pairing a thiadiazole moiety with a 2,3-benzodiazepine scaffold via the N-3 position yields an inhibitor type with >28-fold better potency and selectivity on AMPA receptors than either 2,3-benzodiazepine scaffold alone or talampanel.
Consequently, fucoidan exhibited a better antiviral potency than ribavirin [ 80].
One compound, 62, with an IC50 value of 0.6 μM, displayed better potency than the original chalcone 2 against the strand transfer process.
Following i.p. administration to rats OM-TMCD demonstrated a broad spectrum of anticonvulsant activity and showed better potency than VPA in the maximal electroshock seizure and subcutaneous pentylenetetrazole tests as well as in the hippocampal kindling model.
Particularly, compound 7d was found as an excellent STAT3 inhibitor with over 50-fold better potency than resveratrol and caffeic acid.
Compound 16 functioned as a DNA non-intercalative topo IIα catalytic inhibitor with better potency than etoposide in T47D breast cancer cells.
