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Palladium presented then a better affinity for FAU zeolite and copper oxide had a better affinity for zirconia.
CALB showed a better affinity for 1,4-butanediol compared to 1,3-propanediol (1,3-PDO), whereas no preference was observed between diethyl succinate and diethyl adipate.
The catalytic efficiency of StyB from strain ST is comparable to that of StyB from strain 1CP, mainly because of a better affinity for both NADH and FAD (Table 2).
Although the K m values showed that TH2-CP had a better affinity for Z-Gly-Leu than for Z-Gly-Gly-Leu, the V max values showed that Z-Gly-Gly-Leu was hydrolyzed faster than Z-Gly-Leu.
The structure of various additional positively and/or negatively charged groups attached to the N- and C-termini of TCOs had a pronounced effect on their interaction with the DNA substrate complexed to IN. Modified TCOs having a better affinity for this complex should provide a rationale for the design of drugs targeting the integration step.
Indeed as shown in fig 2, IntI1 had a better affinity for the dsattI1 and the single-stranded bsattC while this enzyme only poorly bound the dsattC site.
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This can be interpreted as a better affinity of cholesterol for anandamide than for unsaturated fatty acids such as the arachidonic acid.
The K m and V max values shown in Table 3 indicate that TH2-CP has a better affinity and reactivity for Z-Gly-Leu than for Z-Gly-Phe.
By contrast, mAb 2G11, which was engineered for better cross-reactivity than ING1, has a much better affinity for both BoNT/A1 and /A2 (Table 1) and shows a high level of inhibition against both toxins.
"You're getting a lot better affinity for the brand if you're doing things this way," someecards co-founder Duncan Mitchell tells us.
These results suggest that OHCbl responsiveness in patients with the R161Q mutation is due to a combination of better affinity for OHCbl than CNCbl and a much better stabilisation of the mutant protein by OHCbl.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com