From our own experience in a small cohort (unpublished data), apparent diffusion coefficient (ADC) values in the cystic areas of a benign struma are high, while the solid areas present with ADC values within the benign range.
The 10 studies included a total of 895 patients (range 29 329) with a total of 1264 breast lesions (range 33 469) of which 606 were classified as malignant (range 9 279) and 658 as benign (range 22 190) [ 20– 29].
On average, small cancers were not as stiff as larger cancers but not to the extent of bringing the stiffness values down to the benign range.
The vast majority of these lesions are benign, ranging from benign cysts to complications of underlying diseases and many of them demonstrate characteristic features on MRI, thus allowing a confident diagnosis to be made [1, 2, 3, 4, 5, 6].
Epstein Barr virus (EBV) commonly infects young adults and manifestations range from a benign course to infectious mononucleosis (IM).
It can represent a wide spectrum of conditions, ranging from a benign and self-limiting disease to a surgical emergency.
However acute abdomen can represent a wide spectrum of conditions, ranging from a benign and self-limiting disease to a surgical emergency.
In addition, comparing event rates is also challenging and potentially misleading as definitions of ADEs are unclear among studies, ranging from a benign and transient alteration of electrolytes to vital organ damage.
In fact, CE and/or PI, unexplained by a clear concomitant benign pathology, ranged from 0% for CA15.3 to 17% for MCA with ≥ 11 cut-off value.
Germline mutation of LKB1 causes Peutz-Jegher's syndrome, a multiple hamartoma syndrome with a range of benign tumours including a few in the ureter and bladder [ 81].
Large deviations from physiologically benign growth range can divert resources from vital body functions and cause developmental defects, thereby constraining the welfare and productivity of animals.
