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Therefore, if these sequences really represent divergent paralogs, it is not clear, whether they underwent non-functionalization (silencing by degenerative mutations), neofunctionalization (non-synonymous substitutions providing a beneficial function) or subfunctionalization (partitioning of ancestral functions between duplicates) [ 70].
Our results fit with the compensatory account9,10,27 that the additional activity in speech motor regions presented a beneficial function in supporting task performance.
The sliding poses a threat to the built environment, of course, but it also has a beneficial function, according to Richard Allen, the director of the Seismological Laboratory at the University of California, Berkeley, which sits not far from the fault.
Apart from warming the hearts of retirees who make an old-fashioned distinction between principal and income, dividends serve a beneficial function in braking executives' penchant to squander corporate resources.
Trying to define beauty, Changeux summarizes views from Plato onward, singling out Plato's dialogue "Greater Hippias," from which he extracts two definitions: "formal appropriateness, where the unity of the whole triumphed over the multiplicity of its parts," and more especially, the harmony of those parts in the service of a beneficial function.
In HIV-1 infection, Tregs probably have a beneficial function by limiting the damage of immune activation [32], [33], [34], [35].
Similar(42)
Examples of these UAG actions include improvement of pancreatic β-cell function and survival [5], [6], and a beneficial role in cardiovascular function [4], [7].
These findings provide the first evidence to our knowledge that genistein may play a beneficial role in vascular function through targeting the PKA/CREB/eNOS/NO signaling pathway.
In the context of high oxidative stress, the reaction with superoxide exacerbates cellular derangements by removing NO, which would play a beneficial role in several functions in the heart, and by producing ONOO−.
51 From an evolutionary point of view it is difficult to understand that expression of a potentially harmful protein without a clear beneficial function is permitted in a vital organ as the brain.
CONCLUSIONS: We conclude that disruption of CIITA function plays a beneficial role in preventing normal allogeneic T-cell responses.
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