Exact(1)
Prenyl- and pyrano-xanthones derived from 1,3,6-trihydroxy-9H-xanthen-9-one, a basic backbone of gambogic acid (GA), were synthesized and evaluated for in vitro cytotoxic effects against four human cancer cell lines (KB, KBvin, A549, and DU-145) and anti-inflammatory activity toward superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB.
Similar(59)
The original biologic paradigm "the process is the product" is still the basic backbone of a biologic.
Even the basic backbone of the product line, Lego System, comprised a number of subsets, such as Aquazone, U.F.O., ResQ, Castle, Extreme Team, and the daringly antiquated Town and Boats.
Polyethylene is the basic backbone of all alkene polymers, and the other two are the first members of the vinyl polymers which have stereospecifically placed alkyl side chains.
These discoveries, indirectly have opened new areas of research in which pincer compounds have impacted in the last 30 years by the mere change of the substituent on the 4-position (para position) of the aromatic ring on the basic backbone of pincers.
Mitsuda has described their collaborative style as that he would first create the "basic backbone" of the song and form the idea of how he wanted the song "to turn out", then take the result to Ootsuki for them to arrange together.
All fragments were cloned into the pGL3 basic backbone (Promega) digested with the appropriate restriction enzymes.
Figure 1c shows alternative constructs created from this basic backbone.
Different serotypes result from modification of the basic backbone conferred by phage-encoded glucosyltransferase and/or acetyltransferase genes, or plasmid-encoded phosphoethanolamine transferase.
Previous studies on the structural organization of bacterial genomes revealed that basic backbone of genomic core is interrupted by genomic islands.
The -2-kb mouse Cby promoter luciferase reporter in the pGL3-Basic backbone has been previously published [36].
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