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"Just a bad sequence," he said.
"If the pension fund has a bad sequence of returns, all of a sudden it's, 'How are you going to pay this?'" Mr. McShea said.
On Wednesday, Pettitte was asked three times why the curve was the wrong pitch to throw there, but he just kept saying it was a bad sequence of pitches.
"If you have a bad sequence of returns early in retirement, you would have a lower stock allocation when you are most vulnerable to losses," Mr. Pfau said, referring to their approach.
The U.S. paid a steep price for a bad sequence.
Analysis of 'orphan' scaffolds not incorporated into the main chromosomal assembly identified another 14 orphan scaffolds larger than 100 kb showing high hit/kb values comparable to scaffold 7. Of these, scaffold 35 (27 hit/kb) is covered by high-density reads only on 30% of its length, consistent with a bad sequence join.
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What the president had gotten himself into was, "A real mess: bad sequencing, disorganization, a sense of, a lack of real focus and strategy for what the U.S. wants to do in the world".
The coding sequence affects V(D J recombination, thus if the heptamer is flanked by a "bad" coding sequence (such as T or A stretch) the recombination efficiency may decrease [13], [35], [36].
The most likely cause for bad sequence quality is that more than a single product is excised from the gel and sequenced, especially if the target band migrates very close to other bands of nearly similar sizes.
Here, to answer these and other questions, we analyze a data set of high-quality human mRNAs, using an annotation pipeline which insures that spurious frame disruptions (due simply to bad sequence alignment) are discarded.
Our analysis thus helps pinpoint bad sequence joins in the scaffold assembly.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com