The phrase "a background of significant" is not complete and lacks clarity in written English.
It can be used when discussing the context or circumstances that are important or noteworthy, but it needs to be followed by a noun to specify what is significant.
Example: "The study was conducted against a background of significant economic changes in the region."
Alternatives: "a backdrop of considerable" or "a context of notable".
There is a background of significant benign reactive T cell lymphoid hyperplasia.
Furthermore, unlike the previous observations of persistent diet-induced obesity in rats that occurred on a background of significant growth [6] [13], our chow fed mice increased their fat-free mass by less than 5% over the 19 week study.
Progress in both perception and experience of corruption in municipal government occurred against a background of significant legal and fiscal changes during the period of this study.
However, these findings are reported on a background of significant measurement uncertainty associated with the estimation and quantification of these parameters.
This must be interpreted against a background of significant economic expansion [ 28] and increased urbanisation that are likely to have transformed the intrinsic risk of transmission in some areas, to the extent that even if control were interrupted, rebound to historical risks of transmission are unlikely.
Against a background of a significant shadow economy [ 38], people are unwilling to reveal their actual income.
Two of the 44 new confirmed clusters occurred against a background of a significant decreasing trend, and two occurred in association with an increasing trend and may have been a manifestation of that trend.
Here, the main output is the global identification of fluxes strongly correlated with a highly productive state, which are discriminated from a background of less significant metabolic reactions contributing to product synthesis.
It will provide them with a good background of significant factors that can affect the acceptability and effectiveness of this policy in the local context.
Dr Scott Blinder, director of the Migration Observatory at Oxford University, reported a decline in student immigration to the UK since 2010, though this was against a background of a very significant increase from 2007.
Against a background of interplanetary war, Lucky (a doubly significant name) is forced to leave his home planet of Phoenix to find his father, who will hopefully be able to explain why he dreams that the stars are singing to him, and why a luminous, burning power sometimes surges through him as he sleeps so that even his sheets are incinerated.
