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The most commonly reported clinical signs in the cyclosporine A alone group were associated with the digestive tract (47% of all reported clinical signs).
All 48 cases were included in the clinical safety analysis (cyclosporine A alone group n = 25; concurrent treatment group n = 23).
There was no significant differences between the groups in the incidence of skin and appendage disorders, with the exception of pyoderma, which was more frequently reported in the cyclosporine A alone group.
A significantly lower incidence of vomiting was reported for the concurrent therapy group (2 reports in 2 dogs, vs. 13 reports in 10 dogs in the cyclosporine A alone group).
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Cyclosporine treatment to the rats toxic control (Cyclosporin-A alone) group resulted in significant increase in renal tissue (L-MDA) levels as compared with the extract treated groups (p<0.05).
Moreover, SU5614 downregulated the gene expression of Cd31 (P < 0.01) and endothelial-specific nitric oxide synthase (eNos, P < 0.005), compared with the VEGF-A alone group (expression level = 1, Figure 2E).
Patients were divided into four treatment groups: Group A, RT alone; Group B, CCRT; Group C, RT and AC; Group D, CCRT and AC.
This bench study compares the incidence of airway occlusion when using (group 1) no airway humidification, (group 2) a HME alone, (group 3) a HH alone and (group 4) both a HME and a HH in combination.
To determine the role of adjuvant chemoradiotherapy, we are preparing a matched pair study between an adjuvant chemoradiotherapy group and a surgery alone group.
This prospective, open-label, randomized, multicenter study with a group sequential design compared PDT in addition to stenting (group A) with stenting alone (group B) in patients with NCC.
Participants were allocated into two groups based on their preference: behavioral group therapy (group A) and education alone (group B).
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