For example, in 1997, Steinberg et al. estimated the cost for 12 ovarian cancer studies to be $259,300 for conducting an IPD meta-analysis versus $48,665 for an aggregate data meta-analysis [ 78].
In addition, the time and costs associated with conducting an IPD meta-analysis are substantially greater than conducting an aggregate data meta-analysis.
It provides similar notifications to the data sources, for example, notifying an aggregate data source that the current row has started and thus any previous aggregate values should be reset.
Figure 4 contains an aggregate data traffic pattern receiving from all nodes running Map tasks, which is denoted by the solid line and a single data flow transmitted by a typical Map node, denoted by the dash line.
Besides, the transmission rate of 356.3, 312.5, 323.8, and 343.1 Mbit/s was achieved for the four channels, respectively, while the BERs were below the FEC threshold, leading to an aggregate data rate of over 1.3 Gbit/s.
Thus, an aggregate data rate of over 1.3 Gbit/s is realized with the 3-dB bandwidth of 20 MHz, while the bit error rates (BERs) for the four channels are below the forward error correction (FEC) threshold.
An IPD MA offers numerous statistical and clinical advantages over an aggregate data MA 15.
Initially, an aggregate data analysis will be undertaken although treatment effect estimates will be obtained from the individual patient data.
This allowed us to combine protein abundances measured using single-target labeling into an aggregate data set for mathematical modeling.
Furthermore, the time and costs associated with conducting an IPD meta-analysis have been shown to be substantially greater than conducting an aggregate data meta-analysis.
