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In their canonical forms, these nucleases induce double-strand breaks at a DNA locus of interest that can trigger cellular DNA repair processes that disrupt or replace genes.
In this study, we have cloned and sequenced a 24-kb fragment of a DNA locus upstream of the previously reported but incomplete putative ORF9 of L. lactamgenus.
A DNA locus was defined as 'active' if it co-localized with an RNAP spot in 5 9 cumulative frames (user-defined parameter) during the 15-min reaction.
Similar to the earlier release [ 1], it is an event-driven automaton that simulates large combinations of interacting stochastic and deterministic processes in a DNA locus against modeled physical time.
TF-DNA binding avidity: an integrative quantitative characteristic of availability of a DNA locus (e.g. TFBS and its flanking region) for a given protein (e.g. TF) binding Sp: specificity Se: sensitivity: (1- p0)100%.
For a DNA locus, suppose its average DNAm level in myeloid and lymphoid cells are βm and βl, respectively, then the DNAm level in the normal whole blood/leukocytes can be represented as where Pm and Pl (Pl=1− Pm) represent the proportion of myeloid and lymphoid cells in the peripheral whole blood of a normal sample, respectively.
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It is possible that these domains could be transcribed from a distinct DNA locus and the rRNA reassembled post-transcriptionally.
According to the model, a fluctuating DNA locus is captured out-of-equilibrium by the partition complex (via ParA-ATP dimers).
Plant researchers examined several coding and non-coding regions, but they soon realized that a single DNA locus has limited resolving power for closely related species [ 16, 17].
Six plasmids contained a yeast genomic DNA locus, provisionally named DTS1 (DTS = deletion of T GS1 suppressor).
A QTL is a DNA region (locus, pl. loci), harboring a gene or a regulatory element affecting a quantitative trait.
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