Exact(4)
Gestational age was based on a 1st trimester ultrasound scan.
Women were asked to fill out a 1st trimester self-administered questionnaire and were interviewed over the telephone during their 2nd trimester of pregnancy.
Maternal urinary measures of eleven phthalate metabolites and BPA collected from a 1st trimester spot urine sample were available in the MIREC study.
For this analysis, participants were included if they had completed a 1st trimester screening with PAPP-A and human chorionic gonadotropin (hCG) levels and were later diagnosed with either preeclampsia or normal pregnancy.
Similar(56)
All correlations are significant at p < 0.0001; bf = three months before the beginning of pregnancy; t1 = 1st trimester; t2 = 2nd trimester; t3 = 3rd trimester.
Further analysis showed that the 883 probes that increased in methylation from first to third trimester were predominantly those with intermediate methylation levels (average β range 0.3 - 0.5) in the first trimester (Additional file 7). Figure 3 shows a heat map with unsupervised clustering of samples based on the 954 probes showing a Δβ > 0.2 between 1st trimester and term.
One other publication explored the relationship of 1st trimester PAPP-A with 1st trimester sFlt-1 in preeclampsia and normal pregnancies [ 26].
Despite its correlation to 1st trimester PAPP-A, low 1st trimester sFlt-1 did not have the same ability to predict pregnancy outcome.
Cutoff: cutoff value at a fixed FPR of 10%, DR: DR at a fixed FPR of 10%, Cutoff: cutoff value at a fixed FPR of 5%, DR: DR at a fixed FPR of 5%, PAPP-A: pregnancy-associated plasma protein-A, sFlt-1: second trimester sFlt-1, sFlt-1/PlGF: second trimester sFlt-1/PlGF ratio, sFlt-1/PlGF: third trimester sFlt-1/PlGF ratio, SE: standard error.
The 3 measures of iodine-to-creatinine ratio were only moderately correlated, which suggested that a measure in 1 trimester will give minimal information on status at other stages of pregnancy.
Inactivated influenza vaccine is recommended in all 3 trimesters of pregnancy (15, 40 ).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com