Exact(3)
In the present work, compound 4 (kaempferol) did not present any antifungal activity.
Based on this work, compound 27 (omadacycline) was identified for clinical development, with the generic designation omadacycline, and is now entering phase 3 human trials as an intravenous and oral therapy for ABSSSI and CABP.
CH-01 is based on the Chk1 inhibitor 6 reported by Foloppe et al. During the course of this work, compound 6 was also shown to inhibit Aurora kinase A. Inhibitors of Aurora kinases have been tested clinically and show some promise; however, these agents have not been tested specifically in hypoxic conditions.
Similar(57)
"One compound didn't work.
shell fell in the American Legation compound.
She rented a large house near the U.N.H.C.R. compound.
"That's the Kennedy compound over there," he tells her.
Later, angry Germans threatened to break into the K.G.B. compound.
It is the site of a United Nations compound.
"In September 2012, a mob attacked the U.S. Embassy compound.
The only true binary RO compound is EuO.
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