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IGF-II improved a rodent's memory only when administered in a precise window of time roughly within 24 hours after the foot shock which coincides with a stage in the learning process called "memory consolidation". That's a poorly understood transition period when a memory is still malleable but becoming more established and robust.
IGF-2 improved a rodent's memory only when administered in a precise window of time roughly within 24 hours after the foot shock which coincides with a stage in the learning process called "memory consolidation".
Without a precise "window of opportunity", spike generation depends on synaptic summation.
Distractors presented contralateral to a visual target inhibit the generation of saccades within a precise temporal window (Buonocore & McIntosh, 2008; Reingold & Stampe, 2002; Walker, Kentridge, & Findlay, 1995).
This raises the possibility to predict RA development in high-risk populations and may further allow a more precise "window of opportunity" for early and effective treatment interventions.
This suggests that genistein is acting during a precise developmental window around 12 hpf.
Timing experiments demonstrate that apoptosis is induced during a precise developmental window.
This confirms the idea that genistein acts during a precise developmental window up to the beginning of somitogenesis.
The Peak Day method identifies a much more precise window of the periconceptional period than that used in most previous studies of periconceptional exposures.
Evidence has been accumulating that anti-CD3 therapy has a precise therapeutic window for promoting a disease remission (11).
The engineered Fc-nonbinding (crystallizable fragment-nonbinding) CD3 antibody has lower mitogenicity and a precise therapeutic window for disease remission in patients with type 1 diabetes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com