Sentence examples for With reduced efficacy from inspiring English sources

Along similar lines, regions of highly reduced recombination in the Drosophila genome exhibit elevated levels of nonsynonymous polymorphism, consistent with reduced efficacy of selection in these regions (Presgraves 2005; Betancourt et al. 2009).

The major concern regarding reducing or changing the concentration of BP was the possibility that lower concentrations may be associated with reduced efficacy.

Immediate vaccination with a non-clade matched vaccine, even with reduced efficacy, would prevent thousands of new infections in SF and millions in SA over 30 years.

We utilized a mathematical model to determine the effectiveness of immediate roll-out of a non-clade matched vaccine with reduced efficacy compared to constructing clade specific vaccines, which would take considerable time to manufacture and test in safety and efficacy trials.

In addition, headaches recur within a predictable period after the last dose of medication, usually with reduced efficacy.

This is the first description of a mutation from any species affecting the farnesyl pyrophosphate binding pocket with reduced efficacy of PFT inhibitors.

Overall, any prolongation in treatment course is strongly associated with significantly reduced efficacy of C-CRT and therefore reduced rates of locoregional control and survival [ 51].

If patients feel that treatment is not working, adherence is likely to be poor with consequently reduced efficacy of treatment [ 37].

However, the presence of HACA was not associated with IRRs or reduced efficacy upon retreatment.

If gene A performs function f1 and gene B performs both functions f1 and f2, but f1 with a slightly reduced efficacy, this genetic redundancy would be considered as evolutionary stable [ 59].

Diabetic men generally have reduced efficacy with PDE-5 inhibitors (PDE5i) for the treatment of erectile dysfunction (ED).