Our current understanding of the initial pathogenetic steps in IgA nephropathy (IgAN) provides relatively limited rationale for immunosuppressive therapy.
Geering explains that audience members with limited vision see Rationale's breakdancing performances and have their depth perception improved, meaning what may have looked like a television screen to a Visually Impaired viewer suddenly becomes live theatre.
With limited structural information, here we aim to determine the mechanistic rationale for the catalytic enhancement that results from binding of the peptide ligand to the PHD1 domain.
With limited substitution, rosters could be smaller.
The other associated therapeutic options, however, are represented by drugs with limited efficacy or a doubtful physiologic rationale, in that they mainly act on body sodium pool, while it is the water pool that is primarily altered.
In fact, the same rationale and limitation applies to all imaging strategies with limited spatial resolution in the third dimension, including confocal imaging.
Antiplatelet therapy is common in this population and has been associated with increased morbidity and mortality after head injury, but the evidence has been based mainly on pathophysiologic rationales and retrospective analyses with limited patient numbers [ 2].
We based this hypothesis on the rationale that LTNPs and/or patients with limited amounts of time with low CD4 counts would better retain key immunological features, such as lymphoid architecture and T cell homeostasis, and this in turn would allow their CD4+ T cell counts to recover more rapidly.
Each chapter includes an explanation to help managers with limited conceptual knowledge of OR management science to understand the rationale that underlies good decision-making.
This, on the one hand, conflicts with the general rationale that SECaaS is particularly relevant for companies with limited capacities regarding IT security; on the other hand, however, it confirms previous findings regarding the adoption of SaaS [23].
The legal rationale for the move was "prosecutorial discretion" — the concept that law enforcement agencies with limited resources must set priorities.
