Sentence examples for Very demented from inspiring English sources

"It took a village to raise this very demented child," she said.

"It took a village to raise this very demented child and I hope that everyone who was involved feels thanked every single day... Making this show and the response to it has been the most validating thing that I've ever felt; it's made me feel so much less alone in this world.

Participants who were cognitively normal (CDR 0, n = 198), very mildly demented (CDR 0.5, n = 65) or mildly demented (CDR 1, n = 29) at the time of LP were selected without regard to previously measured biomarkers.

Using a multiplexed Luminex platform, 190 analytes were measured in 333 CSF samples from cognitively normal (Clinical Dementia Rating [CDR] 0), very mildly demented (CDR 0.5), and mildly demented (CDR 1) individuals.

Using a targeted proteomic screen, we identified novel candidate biomarkers that complement the best current CSF biomarkers for distinguishing very mildly/mildly demented from cognitively normal individuals.

This study identifies novel biomarkers that improve upon the ability of the best identified biomarkers to date to discriminate very mildly demented from cognitively normal participants, and identifies a novel biomarker with significant prognostic potential.

7, 8, 23, 24 The hazard ratio of death increased from 1.82 for the very mildly demented to 9.52 for severely demented patients.

"They'll be a population of demented very old people, like an invasion of terrible immigrants, stinking out the restaurants and cafes and shops," he said.

"There'll be a population of demented very old people, like an invasion of terrible immigrants, stinking out the restaurants and cafes and shops," he said, before proposing public euthanasia stands: "There should be a booth on every corner where you could get a martini and a medal".

Thus, we utilized statistical machine learning algorithms, which are more amenable to potentially large numbers of analyte combinations and can identify highly complex nonlinear relationships, to discover whether groups of markers are capable of distinguishing very mildly/mildly demented (CDR 0.5 and 1 combined) from cognitively normal participants (CDR 0).

Of the 125 RBM analytes that were statistically assessed (Table S1), the mean concentrations of 37 CSF analytes were found to differ between cognitively normal (CDR 0) and very mildly/mildly demented (CDR 0.5 and 1) participants by analysis of covariance (ANCOVA) adjusting for age and gender (p<0.05) (Table 2 and Table S2).