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Mann-Whitney post hoc calcium variation from baseline to 3 h P < 0.05 vs. group 40.

#Mann-Whitney post hoc analysis, variable variation from baseline to 3 h; P < 0.05 vs. group 40.

Data are expressed as variation from baseline (i.e., ΔEtCO2 for EtCO2 variation) after different volumes of infused fluid: 100 and 500 ml.

Mann-Whitney post hoc analysis chloride variation from baseline to 3 h P < 0.05 vs. group 40 gMixed model timepoint vs. group interaction P = 0.046.

Inhibitory activity was measured as intracellular Ca2+ ([Ca2+]i) flux variation from baseline while in the presence of 100% activating BzATP (100 μM for hP2X7 and rP2X7, 200 μM for mP2X7).

In contrast to the bottle-feeders, breast-feeders evinced a non-significant HR variation from baseline situated within a range of −1.81 and 8.08 beats per minute (bpm) (Figure 4A), a level of variation that is not different from these elicited by all other stimuli (p>.10 in all cases).

Mann-Whitney post hoc analysis of calcium variations from baseline to 3 h, P < 0.05 vs. group 40.

Mann-Whitney post hoc analysis of chloride variations from baseline to 3 h, P < 0.05 vs. group 40.

In cases of relevancy, data were expressed as variations from baseline computed as the difference between final and baseline value divided by the baseline value and expressed as ΔCI and ΔEtCO2 for CI and EtCO2 variation.

Variations from baseline in haematological and biochemistry parameters were comparable between groups (Table  5).

This population was used for analysis of the primary endpoint as well as serum creatinine and eGFR level variations from baseline.