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Because almost all public cancer signatures have only been validated using a few test datasets, a practical question is how to select additional valid datasets for signature validation.
In order to develop an empirical model for hard rock TBM performance prediction with more suitable applicability in China, 49 valid datasets were collected from a water conveyance tunnel mostly excavated in medium to hard igneous rocks, and the empirical relationships between TBM performance and each parameter in the database were studied.
Requires large statistically valid datasets for robust correlations.
Of the 50 randomized patients, two patients in each group dropped out, resulting in 46 available valid datasets.
In recent years, many professional organizations have focused considerable effort on advocating for the use of decision making based on research generated from representative and/or valid datasets.
Investigating centres with variable practice and uptake (high, low or absent) simultaneously can potentially eliminate bias and provide more complementary and valid datasets for comprehensive analysis and interpretation.
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Examining age, gender, and maternal education collectively in this ecologically valid dataset, we find several key results.
Pipeline output: the final valid dataset is in BAM/SAM format, with read pairs constituting a di-tag placed on adjacent lines within the file.
There were no differences between children with and without a valid dataset regarding gender, but the former were slightly older (3.4 ± 0.6 and 3.2 ± 0.7, p < 0.001).
Table 1 shows the characteristics of the 529 children with a valid dataset (i.e. who had complete data for BMI, age, gender and for all 5 motor skills of the Basic Motor Score).
One initial difficulty to overcame is represented by the circular notion that (i) we would like to partition the dataset without splitting the profiles that belong to a unique ncRNA, but at the same time and (ii) we need to have a parametric method to identify the extent of the underlying ncRNAs and the parameters have to be determined on a valid dataset partition.
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CEO of Professional Science Editing for Scientists @ prosciediting.com