Because the antimetabolites act primarily upon cells undergoing synthesis of new DNA for formation of new cells, it follows that most of the toxicities associated with these drugs are seen in cells that are growing and dividing quickly.
However, treatment with 10 µM hippuristanol confers significantly higher viability upon cells undergoing oxidative stress compared with those in which eIF4A is uninhibited (figure 5).
Three-point bending damage to the beam sample can be healed even at a constrained boundary condition upon local heating, undergoing a close-then-heal procedure.
To optimize strength without unduly increasing weight, bones accommodate the loads that are habitually imposed upon them by undergoing alterations in mass, external geometry, and internal micro-architecture.
Unpaired surface cysteines of extracellularly-arrived proteins such as antibodies are uncapped upon secretion before undergoing disulfide exchange with cystine or oxidized GSH in culture medium.
Thus, to limit dropout from further treatment, more effective support may allow the couple an opportunity to reflect upon their options undergoing treatment.
ULVWF multimers are biologically very active [ 2, 31] and, upon release, undergo processing into smaller multimers in normal individuals.
The excited-state population generated upon photoexcitation undergoes productive photoisomerization and fluorescence, with quantum yields denoted by Φphoto and Φfluor, in addition to other nonradiative deexcitation pathways.
