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Specifically, H4K16ac, a histone modification involved in chromatin decompaction, is increased on nascent chromatin upon abolishing Hdacs1,2 activities.
Consistent with this finding, noninvasive transformed cells in vitro become invasive upon abolishing E-cadherin function or expression (Vleminckx et al, 1991).
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Differential expression between constant light and constant darkness upon growth on cellulose was abolished upon lack of BLR1 and BLR2 for all genes investigated, except xki1, which does not show regulation by light in the wild-type.
Chromatin immunoprecipitation assays revealed that lymphoid enhancer factor-1 (LEF1) dissociated from the CYLD promoter upon selenite treatment, thus abolishing suppression of CYLD gene expression.
Immunofluorescence of p-PAK1 revealed cytoplasmic levels of p-PAK1 increased upon TNFα stimulation, and this effect was abolished upon PAK1 kinase inhibition using IPA-3 (Supplementary Fig. S1B).
The repressive culture began to ease in 2008, when Donnie Walsh insisted on abolishing the rules upon becoming team president.
It was finally abolished upon the restoration of the Bourbons.
In December 1640 an orchestrated petitioning campaign called upon Parliament to abolish episcopacy, root and branch.
Can subjecting the perpetrators of such crimes to discomfort akin to that experienced by many of us while giving a blood specimen during a doctor's visit be a responsible basis upon which to abolish the death penalty?
The Supreme Privy Council was abolished upon Anna's accession in 1730, and the functions of coordination, supervision, and policy planning were vested in a cabinet of ministers composed of three experienced high officials, all Russians.
This effect was abolished upon treatment with inhibitors of the p38 MAPK pathway and nuclear factor (NF -κB pathways.
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CEO of Professional Science Editing for Scientists @ prosciediting.com