While this unresolved ménage caused Betjeman much grief and enveloped him (up to a point) in fear of mortal sin, it can make the passing years seem a two-dimensional round of social engagements and name-dropping.
The sequence is: Thoughts attract emotions that, if unresolved, may cause physical problems.
There is speculation that both cancer and aging may occur as a result of damage accumulation and genomic instability, which if unresolved, can cause physiological degradation and contribute to cancer cell formation [ 7].
Non-haematological toxicity (excluding nausea/vomiting) of grade 3 or more, nausea/vomiting of grade 3 or more uncontrolled by aggressive anti-emetic support, grade 4 neutropenia lasting 5 days or more, febrile (⩾38.5 °C) neutropenia of grade 3 or more, grade 4 thrombocytopenia, or unresolved toxicities causing more than a 2-week delay of the next scheduled dose.
WHILE LEAVING MUCH unresolved about the causes of civic disengagement Putnam does provide a satisfactory answer to some previous criticism.
Altogether, our data indicate that chronic HCD feeding impairs UPRER and consequently causes unresolved ER stress that hinders the growth of Kras G12D -driven lung tumors.
Although studies show that multiple pathways can contribute to ER-stress-induced apoptosis (Li et al, 2006), the mechanisms by which unresolved ER stress causes cell death are not fully characterized (Szegezdi et al, 2006; Zhao & Ackerman, 2006).
Surprisingly, whilst extreme transgenic low-lignin phenotypes (e.g. < 15% lignin on a mass basis) show reduced recalcitrance [ 27], none of the natural variation in basic cell wall compositional components (such as lignin and sugar contents) account sufficiently well for this variability in cell wall recalcitrance, leaving its fundamental causes unresolved.
First discovered in April 2014, the issue apparently remains unresolved and has caused cancellation of all hearings in the case since last February.
With only a year to go until Britain leaves the EU, a mounting backlog of unresolved problems is causing business to take evasive action – despite government attempts to buy more time with a transition deal.
