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Post-test imaging provides the ability to verify that the test was performed in the desired location, which improves the reliability of the data and aids in the explanation of unexpected test results.
Additionally, several practical problems related to companion diagnostics are discussed: that is, how unexpected test results are addressed and how strictly the principle of companion diagnostics should be adhered to.
Markers with high segregation distortion, unexpected χ2 test results or null alleles (a_ × ab; ab × a_) that cannot be handled by JoinMap 3.0 were discarded or scored as dominant markers.
The data show an unexpected distribution of test results with narrow peaks just within test targets.
Although the laboratory had a pandemic plan in place, a retrospective evaluation found 3 major variations from plan assumptions: 1) higher peak demand not limited by a case definition, 2) prolonged peak demand because containment attempts continued despite widespread influenza, and 3) unexpected influence of negative test results on public health actions.
The proposed definition of a reportable event for laboratories is: "Any situation considered unusual related to received samples (frequency, circumstances of occurrence or clinical description) OR test results (unexpected number of the same species/subspecies, strain type/subtype or antimicrobial resistance pattern, or failure/uncertainty in diagnostics)".
In deceased donor transplants, the virtual crossmatch has reduced the number of unexpected positive crossmatch tests resulting in improved organ allocation and reduced ischemia and wait times.
Comparison of agreement between non-homogenized and homogenized tissue samples revealed different patterns of test results and unexpected alterations of agreement due to homogenization.
Their article, entitled "Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing" reported no "evidence for serious emotional distress or inappropriate actions," but the test results may not have been as unexpected as the title suggests.
No preoperative test results were so severe or unexpected that the surgical procedure had to be cancelled.
The results were not unexpected, College Board officials said, adding that it is unlikely that test results will show improvement soon.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com