These questions are complicated by important differences in study design and uneven coverage of neuroimaging modality.
However, a significant limitation of this technique is the low density and uneven coverage that may be achieved over vegetated rural environments.
Mr. and Mrs. Clinton's aides have complained all year that the former president has received uneven coverage in the news media, with attention mainly focused on flare-ups and gaffes and not on his daily successful campaigning.
So when you're figuring out, well, just how much coverage do I have for the amount of lanes I can buy, expect that you're going to get really dramatically uneven coverage and account for it in terms of your thinking through these methodological choices.
Illumina short read sequencing used to generate the genomic data also poses a limitation of this study because of its propensity to generate uneven coverage profiles across the genome (e.g., high coverage at certain loci and little to no coverage at other loci) thus possibly influencing the probability of correctly detecting possible gene deletions.
The top hits were extracted and their numbers normalized (Supplementary Figs. S1, S2) to minimize the effect of uneven coverage bias introduced by multiple displacement amplification used in WGA28,30,31, resulting in the data shown in Figure 1C. Figure 1: Evolutionary analyses of Paulinella ovalis-like SAGs.
Although several B. braunii microcolonies remained on the surface after TCEP·HCl treatment, it might have been due to the uneven coverage of the PFDT coating.
Given the measurement difficulties and the uneven coverage of available estimates we do not attempt to derive time trends in these processes, and we make a number of necessarily simplifying assumptions (see "Methods" section).
This dataset has uneven coverage with coverage varying significantly even within a single transcript.
The real world challenges in these datasets include low quality reads and uneven coverage.
A serious problem is the uneven coverage of both species and areas in these data.
