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However, even in the ICHQ2 guideline there is no information explaining how to decide whether the method under validation is valid for its final purpose or not.
The focus of the MEDLINE/PubMed search was on established laboratory tests as well as on newer diagnostic methods, which have been validated recently or are currently under validation (e.g. studies objectively assessing the diagnostic accuracy of different tests).
Several epigenetic targets have been discovered and are currently under validation for different therapies.
The Swarm N e measurements, although preliminary and under validation, are considered nowadays reliable by the reference community.
"We have other laboratory evidence in the California patient that argues against rabies, but the methodology is under validation," he writes in an e-mail.
Our formal modeling is done entirely within the Microsoft SpecExplorer tool to formally describe the specification of the system under validation in the formal notation of AsmL.
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The area under the receiver operating characteristics curve (AUC), under internal validation, was 0.71.
The effectiveness of our approach is finally demonstrated via comparing with other popular methods under cross validation and predicting potential interactions for DTPs under the validation in existing databases.
They evaluated the effectiveness of their approach by comparing with other popular methods under cross-validation and predicting potential interactions for DTPs under the validation in existing databases.
The results show that the mechanism yields good agreement under all validation conditions.
The Area Under Curve validation statistic did not provide a meaningful optimal multiplier for the standard deviation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com