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This study provides a detailed molecular fingerprint for two EPC subtypes: early EPCs (eEPCs) and outgrowth endothelial cells (OECs).
This paper will point out the weaknesses of two EPC Class 1 GEN-2-conformed security protocols, and then proposes our new protocol, which raises the security level and conforms to the EPC Class 1 GEN-2 standards.
Instead of analyzing all EPCs, they differentiated two EPC sub-populations, namely EPCs of monocytic versus hemangioblastic origin.
These two EPC subsets have recently been described and characterized as early-outgrowth and late-outgrowth EPCs, respectively [ 1, 10].
The aim of this study was to provide a thorough, unbiased analysis of the phenotype of the two EPC subsets isolated in vitro; eEPCs and OECs.
However, when comparing eEPCs and OECs, correlation decreased to less than 0.77, demonstrating that these two EPC types differ significantly at the molecular level.
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The purpose of this paper is to give an overview of the current methods of evidence review and dissemination used by the two EPCs producing DERP reports.
Fig. 2 Change of the three EPCs subpopulations number (mean + SD) before and after the NMES sessions.
Passage four EPCs were used as target cells.
On day five, EPC-CFUs were counted in five wells and the average was obtained.
In recent studies two different EPC subpopulations have been described, denoted as early EPCs and late EPCs, with distinct cell growth patterns and ability to secrete angiogenic factors [ 15, 16].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com