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If a gland divides, the cells divide producing two daughter cells of the same type (e.g. a CSC produces two CSCs and a non-CSC produces two non-CSCs).
Under the probabilistic model, a CSC has a 25% chance of dividing into two CSCs and a 25% chance of dividing into two non-CSCs, with a constraint of having a constant number of CSCs in each generation.
Symmetric divisions of a CSC into two CSCs or into two non-CSCs are both given equal probability (25% each).
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Sarsgaard had already appeared in two CSC shows, Uncle Vanya and The Three Sisters, opposite his wife, Maggie Gyllenhaal.
Brabletz et al. proposed the existence of two CSC populations: (i) stationary CSC subpopulation and (ii) migratory CSC subpopulation.
Indeed, for each value of ω CSC or η1 it is possible to find CSCs in both configurations (low and high), while the two CSC states are well characterized by P sy values: black-blue points mark the low CSC concentrations, red-green points the high ones.
The PRT study's findings are based on a survey, distributed to all prisons, and on visits to 15 prisons, including 14 segregation units and four CSCs.
The present study confirms that CSC is clastogenic, cytotoxic, and mutagenic, with little differences in potencies across three CSCs representing three different tobacco products.
For this, we chose nub-9 (Fig. 11a) as the reference CSC and added the remaining five CSCs to a library.
Using the Salmonella mutagenicity assay, we confirmed that the three CSCs are mutagenic, and that the potency is related to the presence of aromatic amines.
G2.2 reduced the expression of all five CSCs markers examined including CD44, CD133, epithelial adhesion molecule (EpCAM), LGR5, C-X-C chemokine receptor type 4 (CXCR-4) by ∼25 55%.
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CEO of Professional Science Editing for Scientists @ prosciediting.com