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The difference between the proximal and the distal CCO (using the lower of the two CCO values) was defined as CCO decrease (Fig. 1).
Lipid extraction was applied to two CcO samples.
It is thought that this pool may serve as a source of copper ions for chaperones that mediate metallation of CcO, which occurs at two CcO subunits encoded by the mitochondrial genome, Cox1 and Cox2 [ 8].
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The exceptions are the nucleoside reverse transcriptase inhibitors lamivudine (3TC), emtricitabine (FTC), didanosine (ddI), and abacavir (ABC), with the former two having a majority of patients with vPhenotypes above the upper CCO, and the latter two with a majority of patients falling between the two CCOs.
The present study is the first on the agreement between three CCO methods and one intermittent bolus-thermodilution CO method during IAH and subsequent fluid loading.
We recorded bioreactance CO (average of five values over a 5-minute period) just after obtaining the pulmonary artery catheter CCO (average of five CCO values over a 5-minute period).
In total, seven CCO-deficient patches of varying size from three patients were genetically analysed and confirmed that each patch was clonally distinct, as evidenced by patch-unique mtDNA mutations (Table 2).
The lambs were randomly assigned to four groups: CCO; COO; LLO; LOO according to the lamb's diet fed in each period.
A validated FFQ was mailed to participants who had answered the RFQ and was returned after completion by 79.6% of study participants in three centers (CCO, USC, and UH).
To verify this possibility, we examined the lipids extracted from two samples of CcO subjected to the reaction with H2O2.
By contrast, the structures of two bona fide CCOs, ACO, and VP14 show two pathways to the iron center, possibly reflecting the need for the two products of the cleavage reaction to be released into different cellular compartments (i.e., membrane vs cytosol).
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