Sentence examples for Two bim from inspiring English sources

In particular, in the BaxΔC complex Bim 'h2' (L152) and 'h3' (I155) residues are contacted only by Bax amino acids L70 and L76 from α2 and α3, whereas in the Bcl-xLΔC complex at least five amino acids (F97, Y101, A104, F105 and L108) from α2 and α3 of Bcl-xL participate in interactions with these two Bim residues.

PLX4720 upregulated the three Bim mRNA species in both fresh isolates.

Real-time PCR for three Bim isoforms was done by Fast SYBR Green Master Mix (Applied Biosystems).

Most HMCL expressed readily detectable levels of all three Bim isoforms EL, L and S (76%).

Closer study revealed seven Bim transcript variants in the cAMP-stimulated IPC cells.

Although this increase was reflected at the levels of the three Bim mRNA species, the ratios of the BimS mRNA to the BimEL and BimL mRNA in both cell lines before and after treatment remained unaltered.

The effect of B-RAFV600E on the expression of the three Bim isoforms was also examined in a cultured melanocyte line that was transfected with cDNA encoding B-RAFV600E.

Nevertheless, the kinetics and sustainability of upregulation of the three Bim isoforms varied from one another, suggesting that the mechanisms responsible for upregulation of the individual proteins may be different.

The expression of all three BIM protein isoforms (extra long (EL), long (L), and short (S)) also increased substantially over time with OKT3 restimulation, whether Fas blockade was applied or not.

Because the three Bim protein variants were all constitutively expressed at low levels in both cell lines, it was not feasible to judge whether enforced expression of B-RAFV600E resulted in downregulation of the proteins.

Consequently, processes requirements are divided in two parts, BIM and currents processes requirements.