Sentence examples for Top loci from inspiring English sources
Results of the top loci are shown in Table 2.
Disappointingly, the previously studied candidate genes have not been among the top loci in these association scans.
We chose to look at a set of 38 SNPs which were the top loci to reach genome-wide significance selected from currently reported genome wide association studies (GWAS) of which 14 had been independently replicated in 2 studies.
We explored the landscape of the genetic associations of the Affymetrix 500 k markers covering BP genes from several angles: single marker analysis followed by replication and meta-analysis, single-marker analysis of the study samples stratified by life-style factors (BMI, smoking and alcohol consumption), as well as haplotype analysis across top loci.
This SNP was ranked among the top loci in GWAS (P < 5 × 10−6).
Rerunning our analysis across the top loci including IGAP's newly discovered loci may uncover new interactions.
Only the top locus on chromosome 5 was associated after Bonferroni correction for multiple testing.
Although the "top" locus on chromosome 5 retained a very low p value for all thresholds, the second and third ranking loci gave p values of >0.01 if any overlap (>0%) or a >50% threshold was used.
Each top locus shows highly differentiation pattern between Tibetan pigs and Chinese lowland animals.
The top locus reported in [ 30], cg16867657, ranked first in our list as well with a p value of 4.65 × 10−37.
Several genome-wide analysis researches have reported that CACNA1C is a top locus associated with schizophrenia and bipolar disorder [ 41, 42].
