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To rigorously assess our method, we integrate previously disparate lines of research on intelligent topic selection and deep vs. shallow judging (i.e., whether it is more cost-effective to collect many relevance judgments for a few topics or a few judgments for many topics).
To rigorously assess erythropoiesis across hiPSC lines, we first characterized general phenotypic features after 10 d differentiation on OP9 stroma and 14 d in erythroid conditions.
To rigorously assess if Golgi staples had only minor effect on secretion, we further tested the rate of transport of collagen-I and MMP2, two proteins secreted by Saos-2 cells.
To rigorously assess the sensitivity of the RA sentinel lines, we treated them with different concentrations of RA for 24 hours, with or without the inverse agonist AGN193109 (Johnson et al., 1995), then performed FACS analysis for CFP expression on dissociated cells.
To rigorously assess the temporal and causal relationships between the acquisition of drug resistance and the induction of drug transporters and drug accumulation defects in vitro, we selected MCF-7 breast tumour cells for survival in increasing concentrations of paclitaxel, docetaxel, doxorubicin, or epirubicin.
And importantly, longitudinal studies will be needed to rigorously assess effectiveness of programs for teaching and measuring leadership skills.
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As such, we did not incorporate existing validated measures of HIV stigma into the scheduled study assessments, which would have allowed us to more rigorously assess stigma among our participants and directly compare our findings to prior published work.
To more rigorously assess which genes may have been subject to LGT we used phylogenetic analysis, in conjunction with parsimony analysis [9].
These predictions also permitted us to develop starting dimer S-MB models for MD simulations to more rigorously assess protein-protein interactions (see below).
While visual assessment suggested uniformity, we used these values to more rigorously assess this.
My co-authors and I used such an approach to more rigorously assess the likelihood of recent runs of record-breaking temperatures.
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