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All these mutations of Gne gene result in different altered enzymatic activities [15] [18], which should lead to lessened status of cellular sialylation or at least reduced sialylation of specific glycoproteins, such as α-dystroglycan [19], [20], NCAM [21], neprilysin [22] or aberrant activity of global systems like lysosomal activity and trafficking [7], [23], [24].
Though consumer prices were rising, Bernanke feared a possible bout of deflation — the potentially devastating phenomenon in which prices drop, leading to lessened business activity and then still lower prices and so forth.
In 2000, when the left-of-center Institutional Revolutionary Party lost the presidency and its 71-year grip on power, there were hopes for reform, but it remains to be seen whether increased democratization will lead to lessened corruption.
Johns Hopkins Arthritis Center and Cleveland Clinic echoed that, but both noted that cracking your knuckles has been linked to lessened grip strength over time.
And more importantly, they'll have saved a ton of paper and water due to lessened use of disposable plates and dishwashers.
The Sprint decision comes amid a number of other proposed mergers, including a proposed Comcast Time Warner Cable combination that has some fretting about consolidation leading to lessened competition.
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Polymeric stents can be considered as an alternative to metallic stents thanks to their lessened incidence of restenosis and controlled deployment.
It is not clear whether that fight led to a lessened emphasis on quality, but in recent years Andersen appeared to be more likely than it peers to be involved in failed audits.
Elsewhere, people refused to be distracted by what they saw as the latest stop on the local train to a lessened conflict, if not peace.
However, CXCR7 inhibition raises the concentration of CXCL12 in the mouse bloodstream and blocks CD11b+ cell migration into CXCL12-filled air pouches, presumably owing to a lessened CXCL12 gradient (Berahovich et al, 2013), raising the possibility that CXCR7 inhibitors could block CD11b+ monocyte migration into irradiated tumours in an indirect manner.
Worsted cloth allows for greater speed, but is rarely used outside of professional tournaments due to its lessened durability and price.
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