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Dictionary
To imputation
noun
The act of imputing or charging; attribution; ascription.
Exact(60)
Note, in this scenario, nij may not be an integer due to imputation probabilities being reported rather than imputed genotypes.
Although we assumed that all discrepancies between the imputed and sequenced-derived genotypes were due to imputation errors, it is clear that discrepancies could also be caused by sequencing errors.
Multiple imputation is also employed to assess the uncertainty due to imputation since results based on imputation alone, especially when linking imputed locations to other spatial data, may be questionable.
Our analyses suggest that this approach to imputation can realistically capture regional variation in forest composition.
A common approach to imputation is based on linear regression analysis.
A parametric modeling approach to imputation was initially considered but having data at just two depth intervals led us to non-parametric approaches.
Irrespectively of the existing spectrum of techniques, the results of imputation are commonly numeric meaning that once the data have been imputed they are not distinguishable from the original data being initially available prior to imputation.
Genotyping data were compared to imputation data derived from Illumina HumanHap300 chip genotyping.
Therefore, the observed distortion was due to imputation error and the statistically skewed SNPs (Fig. 2B) are false positives.
It is important to note that the traditional genome inflation factor λ is not an ideal indicator of potential problems related to imputation quality.
This conclusion agrees with that of Guan and Stephens, who indicated that imputation-based methods could be robust to imputation AR and could improve power to detect associations even when average imputation accuracy was not perfect.
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