Sentence examples for To further optimisation from inspiring English sources

Therefore, we have designed and synthesised a novel chemical compound with great potential to further optimisation as inhibitor of drug efflux pumps.

The understanding of the physics of the coolant flow inside the device may hold the key to further optimisation of engineering designs.

Better knowledge of the pathways of cell death, growth arrest and premature senescence induced by cryotherapy in combination with chemotherapy will lead to further optimisation of these combination schedules to achieve a better clinical response.

On the basis of these findings, we believe that AGC can provide a survival benefit for patients with resectable cholangiocarcinoma, and identification of biomarkers that could predict the clinical outcome of AGC may contribute to further optimisation of adjuvant chemotherapy for cholangiocarcinoma.

These methods allow access to greater synthetic diversification and have enabled the synthesis of compounds that have and will continue to facilitate further optimisation of the AF chemotype into a drug-like lead.

A satisfactory compromise is described here although some features of the method remain open to significant further optimisation.

However, there is still need for further optimisation to increase the space time yield, to achieve higher final concentrations and to use a broader range of low cost sustainable raw materials.

This contrasts with eflornithine, a cytostatic HAT drug (s=4.0) which requires only three times its EC50 to obtain EC99.[ 4] Therefore, -(1 R -U504880488 (1) R -U50488furequirestimisation to achieve efurther.

The increased level of competitiveness in all industrial sectors, exacerbated in the last years by the globalisation of the economies and by the sharp fall of the final demands, are pushing enterprises to strive for a further optimisation of their organisational processes, and in particular to pursue new forms of collaboration and partnership with their direct logistics counterparts.

These data suggest that although sensitive, the assay could benefit from further optimisation to reduce primer-dimer formation in negative controls and to increase efficiency.

The V.2 panel would benefit from further optimisation to achieve 100% coverage.