Sentence examples for To ddp from inspiring English sources

While some saw readiness work as a 'lead-in' to DDP, others saw this work as an integral part of a DDP model: I would always start off by doing some work with the carers first because you need to know that they are not going to abandon a child emotionally in a session and that the child is going to be supported.

These data suggest that the concurrent administration of TAM and DDP may result in a delay in the development of resistance to DDP which may have important clinical implications in the design of DDP-containing regimens.

Therefore, downregulation of miR-224 could reverse the DDP resistance of DDP-resistant LA cells by inducing cell arrest in G0/G1 phase and apoptosis enhancement when exposed to DDP treatment.

Furthermore, fNDs DDP treatment improved drug safety compared to DDP treatment.

In this study, we investigated the effect of siRNAs on expression of p-gp, GST-pi mRNA and protein in cisplatin-resistant human ovarian cancer cells in order to restore sensitivity to DDP.

An orthotopically transplanted human ovarian cancer HOC 8 growing in the peritoneal cavity of nude mice was used that is insensitive to Yondelis alone and only moderately sensitive to DDP alone.

These data suggested that miR-224 expression in tumour tissues was negatively correlated with p21WAF1/CIP1 expression and responses of LA patients to DDP-based combination chemotherapy.

Thus, miR-224/p21WAF1/CIP1 signature might predict the responses of LA patients to DDP-based chemotherapy and represent potential targets for therapeutic intervention.

This result indicates that the reduction of the net transcriptional activity of dE2F factors due to dDp-mutant context rescues rbf1-induced loss of tissue.

In the present study, we demonstrated that miR-224 could promote DDP resistance of LA cells via regulating G1/S cell cycle transition and apoptosis by targeting p21WAF1/CIP1 and predicting poor response of LA patients to DDP-based chemotherapy.

To investigate the correlation between miR-224/p21WAF1/CIP1 dysregulation and response to DDP-based chemotherapy and prognosis of patients, the expression of miR-224 and p21WAF1/CIP1 mRNA or protein was detected in a total of 64 LA patients (stage IIIB or IV) who received DDP-based combination chemotherapy combined with docetaxel, gemcitabine or vinorelbine.